The Partnership for Economic Inclusion 2021 Annual Report details the operational activities of the Partnership for Economic Inclusion (PEI) Multi-Donor Trust Fund (MDTF) from July 2020 through June 2021. It has been a pivotal year for PEI, establishing efforts to support the scale up of government-led economic inclusion, in partnership with diverse stakeholders, funding partners and World Bank Group (WBG) operations. As governments and development partners seek solutions to strengthen resilience and recovery, economic inclusion programs are on the rise. The 2020 Annual Report summarizes PEI’s progress toward the adaptation of scaled government-led economic inclusion programs, the promotion of evidence-based learning across government and partner organizations, and the strengthening of partnerships and alliances across PEI to support the ongoing expansion of economic inclusion programming. Results have been strong.